Li CM#, Cordes A, Oliphant M, Quinn SA, Thomas M, Selfors LM, Silvestri F, Zoeller JJ, Shapiro H, Tsiobikas C, Gupta K, Pathania S, Regev A, Kadoch C, Muthuswamy SK, Brugge JS#. (2024) Brca1 haploinsufficiency promotes early tumor onset and epigenetic alterations in a mouse model of hereditary breast cancer. Nature Genetics, 56(12), pp. 2763-2775. (# co-corresponding authors) [PMID: 39528827][News & Views][Press Release]

Gray GK*, Li CM*, Rosenbluth JM*, Selfors LM*, Girnius N, Lin J-R, Schackmann RCJ, Goh WL, Moore K, Shapiro HK, Mei S, D’Andrea K, Nathanson KL, Sorger PK, Santagata S, Regev A, Garber JE, Dillon DA, Brugge JS. (2022) A human breast atlas integrating single-cell proteomics and transcriptomics. Developmental Cell, 57(11), pp. 1400-1420.e7. (* co-first authors, alphabetical) [PMID: 35617956]

Rauner G, Jin DX, Miller DH, Gierahn TM, Li CM, Sokol ES, Feng Y-X, Mathis RA, Love JC, Gupta PB, Kuperwasser C. (2021) Breast tissue regeneration is driven by cell-matrix interactions coordinating multi-lineage stem cell differentiation through DDR1. Nature Communications, 12(1), p. 7116. [PMID: 34893587]

Li CM, Shapiro H, Tsiobikas C, Selfors LM, Chen H, Rosenbluth J, Moore K, Gupta KP, Gray GK, Oren Y, Steinbaugh MJ, Guerriero JL, Pinello L, Regev A, Brugge JS. (2020) Aging-associated alterations in mammary epithelia and stroma revealed by single-cell RNA sequencing. Cell Reports, 33(13), p. 108566. [PMID: 33378681]

Rosenbluth JM, Schackmann RCJ, Gray GK, Selfors LM, Li CM, Boedicker M, Kuiken HJ, Richardson A, Brock J, Garber J, Dillon D, Sachs N, Clevers H, Brugge JS. (2020) Organoid cultures from normal and cancer-prone human breast tissues preserve complex epithelial lineages. Nature Communications, 11(1), pp.1711–14. [PMID: 32249764]

Hamza B, Ng SR, Prakadan SM, Delgado FF, Chin CR, King EM, Yang LF, Davidson SM, DeGouveia KL, Cermak N, Navia AW, Winter PS, Drake RS, Tammela T, Li CM, Papagiannakopoulos T, Gupta AJ, Bagnall JS, Knudsen SM, Vander Heiden MG, Wasserman SC, Jacks T, Shalek AK, Manalis SR. (2019) Optofluidic real-time cell sorter for longitudinal CTC studies in mouse models of cancer. PNAS, 116(6), pp. 2232–2236. [PMID: 30674677]

Gocheva V, Naba A, Bhutkar A, Guardia T, Miller KM, Li CM, Dayton TL, Sanchez-Rivera FJ, Kim-Kiselak C, Jailkhani N, Winslow MM, Rosario AD, Hynes RO, Jacks T. (2017) Quantitative proteomics identify Tenascin-C as a promoter of lung cancer progression and contributor to a signature prognostic of patient survival. PNAS, 40(28), pp. 201707054-E5634. [PMID: 28652369]

Muzumdar MD, Dorans KJ, Chung KM, Robbins R, Tammela T, Gocheva V, Li CM, Jacks T. (2016) Clonal dynamics following p53 loss of heterozygosity in Kras-driven cancers. Nature Communications, 7(1), p. 12685. [PMID: 27585860]

Li CM, Gocheva V, Oudin MJ, Bhutkar A, Wang SY, Date SR, Ng SR, Whittaker CA, Bronson RT, Snyder EL, Gertler FB, Jacks T. (2015) Foxa2 and Cdx2 cooperate with Nkx2-1 to inhibit lung adenocarcinoma metastasis. Genes & Development, 29(17), pp. 1850–1862. [PMID: 26341558]

Li CM, Chen G, Dayton TL, Kim-Kiselak C, Hoersch S, Whittaker CA, Bronson RT, Beer DG, Winslow MM, Jacks T. (2013) Differential Tks5 isoform expression contributes to metastatic invasion of lung adenocarcinoma. Genes & Development, 27(14), pp. 1557–1567. [PMID: 23873940]

Yu B-B, Moffatt BE, Fedorova M, Villiers CGS, Arnold JN, Du E, Swinkels A, Li CM, Ryan A, Sim RB. (2013) Purification, quantification, and functional analysis of Complement Factor H. Methods in Molecular Biology (Clifton, N.J.), 1100, pp. 207–23. [PMID: 24218262]